产品货号：
Z33390
中文名称：
BCL6抗体
英文名称：
Anti-BCL6 Antibody (Clone#OTI13H4)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BCL6 Antibody (Clone#OTI13H4) |
| 指标别名 | B cell CLL/lymphoma 6;B cell lymphoma 5 protein;B cell lymphoma 6 protein;BCL6;LAZ3;Protein LAZ 3;ZBTB27;Zinc finger protein 51;ZNF51 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | BCL6 |
| 克隆号 | OTI13H4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 1-300 of human BCL6 (NP_001697) produced in E.coli. |
| 实际分子量 | 78.7KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | B-cell lymphoma 6 protein is a protein that in humans is encoded by the BCL6 gene.Like BCL2,BCL3,BCL5,BCL7A,BCL9 and BCL10,it has clinical significance in lymphoma.The protein encoded by this gene is an evolutionarily conserved zinc finger transcription factor and contains an N-terminal POZ/BTB domain.This protein acts as a sequence-specific repressor of transcription and has been shown to modulate the STAT-dependent Interleukin 4 (IL-4) responses of B cells.This protein can interact with several corepressor complexes to inhibit transcription.This gene is found to be frequently translocated and hypermutated in diffuse large B cell lymphoma (DLBCL) and contributes to the pathogenesis of DLBCL.An exon 7 skipping splice variant encodes a shorter form of the protein which lacks the first two zinc fingers of the DNA binding domain. |
| Uniprot ID | P41182 |
| 基因名全称 | B-cell CLL/lymphoma 6 |
| 蛋白名全称 | B-cell lymphoma 6 protein |
| 推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索：BCL6抗体，BCL6单抗，Anti-BCL6 Antibody (Clone#OTI13H4)